IMRT
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IMRT
Intensity-Modulated Radiotherapy (IMRT)
- Definition: An advanced form of 3D conformal radiotherapy where the intensity of each radiation beam is modulated to conform the dose to the shape of the tumor.
- Technique: Uses inverse planning and multileaf collimators (MLCs) to deliver non-uniform beam intensities from multiple angles.
Key Features
Feature
Description
Dose Modulation
Delivers different intensities within each radiation beam
Planning
Computer-optimized inverse planning
Beam Angles
Typically 5–9 fixed beam angles
Delivery
Static beam (step-and-shoot or sliding window) or rotational (VMAT)
Applications
Head & neck, prostate, CNS, GI, GYN, breast, thoracic cancers
Advantages
- High conformality around irregular tumor shapes
- Better sparing of nearby normal organs (OARs)
- Allows dose escalation to tumors while reducing toxicity
Limitations
- Longer treatment time than 3D-CRT (shorter with VMAT)
- More complex planning and QA